Problem description

Flow cytometry on 29 healthy and 21 infected individuals. For healthy individuals, measured proportions of cells of 5 different types once. For infected individuals, measured proportions 3 times at different stages in the infection. Scientific question is to understand differences between healthy and infected individuals and temporal changes in the infected group in cell type proportions.

Consulting response

A repeated measures MANOVA is one possible approach to analyze the infected individuals. We would typically use SAS to fit models like these. It appears you can do a repeated measures MANOVA, but this may not allow an appropriate correlation structure for both healthy and infected individuals.

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27 September 2018